Solid/Semi-Solid Dosage

Improved characterization of twin-screw extrusion enables increasing use in pharmaceutical manufacturing.

Sepha's VisionScan Max can leak-test full production batches of blister packs.

Vacuum-conveying conditions for powders and other free-flowing solid forms can be simulated in Volkmann's new laboratory.

Electronic pharmaceutical tablet counters meet demands for accuracy, flexibility, speed, compact size, easy cleanability, and quick changeover.

ACG Worldwide discusses current and future uses of capsules in a video interview with Pharmaceutical Technology.

L.B. Bohle discussed tablet coating in a video interview with Pharmaceutical Technology.

The agency publishes guidance on the physical attributes of generic tablets and capsules.

Nic Michel, General Manager of Pharma Technology, Inc., spoke with Pharmaceutical Technology about the application of external lubrication in tablet production.

PAT holds the key to real-time quality assurance and consistent product quality in pharmaceutical manufacturing.

Box-Behnken modeling was used to optimize a resinate complex, to mask the taste of levocetirizine dihydrochloride and montelukast sodium in orally disintegrating tablets.

Appropriate feeding equipment can be selected to meet the challenges of dosing powders that are sticky or do not flow well.

Economic benefits, equipment availability, research results, and FDA support are driving progress in continuous processing.

Adjusting the tablet press and its systems can prevent manufacturing and product quality problems.

A core coating module allows Roeltgen's FlexiTab development and small-batch tablet press to manufacture multi-layer and externally lubricated tablets.

Innovations for tablet tooling and presses improve quality and productivity.

Quality-by-design tools improve efficiency in scale-up of pharmaceutical processes.

In-silico design facilitates process optimization and evaluation of process control strategies.

A drug-product manufacturing classification system (MCS) for oral solid-dosage forms is proposed by an Academy of Pharmaceutical Sciences working group.

Penn Pharma's equipment addition meets growing need for continuous dry granulation and for handling of highly potent drugs.

Innovative equipment, analytical techniques, software, and modeling systems are improving the tableting process.

Taste may be subjective, but it is crucial to patient compliance, particularly for pediatric treatments.

Analytical technologies must accurately identify and measure the critical material attributes of APIs and excipients.

PAT has aided formulation, both pre-and post-filing, by reducing costs and time frames.

Ionic liquid technologies offer a new way to improve bioavailability.

New cellulosic polymers have been shown to improve solubility in these key amorphous solid dispersion processes.

While the skin offers an alternative route of administration for local and systemic drug delivery, developing semi-solid dosage forms can be a challenge.

MG America's TEKNA Capsule Filler has advanced controls to reduce powder loss and maintain optimal performance.

Tooling can be damaged by poor handling or problems in process design or material choice.

FDA funded projects at Rutgers' C-SOPS and at UMass Lowell to develop flow-sheet model algorithms for use in risk assessment, and start-up company Continuus Pharmaceuticals is making progress on their integrated system.