Facility Design and Engineering

In OSD continuous manufacturing, flexible batch sizes can optimize supply, but equipment and processing challenges are still being addressed.

When specifying an automated powder transfer system for vacuum conveying of pharmaceutical powders, consider material properties, facility constraints, and designs to mitigate explosion.

Sticking and picking are common problems in tablet manufacturing. Considering tablet compression issues before tablet designs are finalized can prevent unanticipated problems during scale-up and full-scale production.

The Pharma Services business of Thermo Fisher Scientific will invest $150 Million at three facilities.

The acquisition of the site in Copenhagen, Denmark, will significantly expand Fujifilm’s capacity and capabilities.

Process optimization improves process mass intensity, reduces environmental impact, and improves cycle time for bio/pharmaceutical processes.

The new facility, located at the company’s headquarters in Pittsburgh, PA, is expected to meet all clinical and commercial development needs of the company’s lead gene therapy program.

FDA guidance on quality considerations for continuous manufacturing should help advance implementation by providing clarity and giving companies more confidence to make investments in the new technology.

The Tandem 4.0 augmented reality-enhanced collaboration tool from Apprentice.io has a new user experience and user interface design.

New technologies in the digital factory enhance quality, efficiency, and flexibility for bio/pharmaceutical manufacturing.

Eli Lilly and Company experts share the vision and the value of the digital plant for pharmaceutical manufacturing.

System connectivity and data analysis drive increased productivity in pharma manufacturing.

Suppliers address complex supply chains for global biopharmaceutical manufacturing using disposable components.

The company will invest an additional $60 million to expand its manufacturing facility in Durham County, NC.

Storage and retrieval methods and the unique requirements found in building codes are crucial considerations.

G-CON will provide a complete cleanroom infrastructure for GE Healthcare’s cell therapy and viral vector production platforms that will simplify early-stage manufacturing efforts.

Modular and podular laboratory and manufacturing allow rapid reconfiguration to support development of drugs for diverse patient populations.

Boulting’s inspection software is a paperless, cloud-based system for maintenance of equipment in hazardous areas.

Digital tools, such as building information modeling (BIM) software, improves efficiency for optimizing pharmaceutical facility design.

Process architects for pharmaceutical manufacturing facilities must understand cGMPs and how to optimize a design for equipment, processes, and people.

Capital Recovery Group, Federal Equipment Company, Heritage Global Partners, and PPL Group purchased a 110-acre campus with a flexible pharmaceutical manufacturing and packaging facility from a generics manufacturer in Huntsville, AL.

TrendMiner 2018.R2 software for analysis of time-series data includes the ContextHub platform for expanded, self-service analytics capabilities.

The SafeGuard Preventative Maintenance Solution from PSG’s Griswold provides remote monitoring for a centrifugal pump and its motor.

The company is investing approximately $14 million to expand biologics packaging capabilities and capacity at its biologics manufacturing facility in Bloomington, IN.

The company will use GE Healthcare’s off-the-shelf KUBio biologics factory, which is expected to start operations in 2020, to provide development and manufacturing for early- to late-clinical and early-commercial manufacturing stages.

Integration of two separate chromatography data systems boosts workflow efficiency.

FDA’s 21st Century goals can be realized by using a multi-purpose manufacturing facility with a flexible design that provides reliable production without extensive regulatory oversight.

The new center will integrate biologics drug discovery, development, clinical manufacturing, and commercial manufacturing.

FDA has issued a warning letter to Mylan citing GMP violations of finished pharmaceutical products manufactured at the company’s Morgantown, WV, facility.

Pharmaceutical manufacturers must stay compliant with changing regulations for hazardous waste disposal.