Manufacturing Equipment, Downstream Processing

The $21.4-billion acquisition will create stand-alone business within Danaher’s life-sciences portfolio.

Parker Bioscience Filtration added a cleanroom at its site in Birtley, UK for manufacturing single-use assemblies and sensors used in biopharmaceutical processing.

Requirements for virus filtration must be considered in developing continuous downstream processes.

The investment builds on a collaboration the companies entered into in 2007 for various biomanufacturing projects.

GE’s new facility, which will be operational in 2019, will produce a fiber-based chromatography platform for more efficient biopharmaceutical purification.

The companies partnered to build a 500-L single-use pilot-scale plant for biologics production.

A collaboration using Pall’s bioprocessing technology in G-CON’s PODs enables flexible continuous bioprocessing and viral vector facility solutions.

The new features on the purifier deliver additional sizes and sterilization/sanitization compatibility.

Modular manufacturing systems offer a less costly way to increase capacity while reducing time-to-market.

The media, by Tosoh Bioscience, is composed of calcium and phosphate buffers and offers mixed-mode properties for biomolecule purification.

The acquisition of Flex Concepts adds custom, single-use products to Entegris’ single-use bag product line.

Traditional barriers between upstream and downstream bioprocessing are slowly starting to break down, as biopharma embraces more advanced analytics and process control.

The new resin used a combination of “jetting” technology and a high-performance Protein A ligand.

The company’s next-generation ultraperformance liquid chromatography platform is designed to meet the evolving laboratory requirements for chromatographic performance.

Parker Bioscience will expand laboratory, cleanroom, office, and warehouse facilities at its Birtley, UK manufacturing site.

The event, taking place on June 6–7, 2018 in Clinton and Somerville, NJ, will focus on the latest melt extrusion and granulation technologies for pharmaceutical and nutraceutical products.

The new Acquity Arc Bio System by Waters is specifically engineered to enable efficient transfer and improvement of bioseparation analytical methods.

Proper selection and installation optimizes fluid system performance.

MilliporeSigma will collaborate with IPS and G-CON to offer end-to-end, turnkey, modular MAb manufacturing.

The company’s new modules offer scalable single-pass diafiltration and were exclusively showcased during its Leadership Forum series in Westborough, MA.

The $72-million investment, part of a larger $850-million investment into its US operations, will allow the drugmaker to replace an outdated insulin vial-filling line and to upgrade technology at its Indianapolis manufacturing plant.

Industry experts discuss the single-use revolution and changes to upstream and downstream processing equipment.

The company added new products to its InfinityLab LC Series which will be showcased at HPLC 2017 in Prague.

Recipharm is investing more than EUR1.2 million to enhance its small-scale GMP API development and manufacturing capabilities in Paderno Dugnano, Italy.

Novasep’s BioSC Lab chromatography is a flexible equipment that enables operations from one column up to six columns in batch, parallel batch, or continuous processing with all media and membrane types.

CMOs experiment with new filtration and purification methods to alleviate downstream bottlenecks and stay competitive.

Industry experts discuss recent trends in modular manufacturing.

Irvine Scientific’s new product range includes chemically-defined, serum-free media, to increase productivity of viral vectors and recombinant proteins in suspension cultures.

CMOs are working hard to improve performance by investigating new technologies for filtration and purification.

This paper describes a unique Prep-rP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a hydrophobic quaternary ammonium salt or quaternary phosphonium salt that acts as an additional/surrogate stationary phase (AsP/ssP).