Manufacturing Equipment, Downstream Processing

The separation of deamidated capsids from non-deamidated capsids can be achieved using HIC, according to studies done by a team at Oxford Biomedica.

A look at the newest innovations offers a deeper understanding of affinity ligands and their role in the future of downstream processing.

Purolite and Repligen have commercially launched a new CH1 affinity resin for the purification of specialized mAbs.

The 3M Harvest RC Chromatographic Clarifier, BT500 is the latest addition to the company’s chromatographic clarifier portfolio.

SCHOTT now offers ViewCell, a new component meant to add flexibility to biopharmaceutical process control.

Sartorius BIA Separations and Teknova will collaborate to combine their technologies in an effort to streamline the downstream purification process.

Freudenberg Medical’s Heflix TPE tubing is a high purity TPE intended for bioprocessing applications.

Automation enables intensification of downstream processes.

Merck has entered into a collaboration with Agilent Technologies with the aim of filling the industry gap in PAT for downstream processing.

PharmTech interviewed Sartorius about SUS innovations and trends.

Simple, inexpensive real-time analytics are urgently needed for high value products.

GEA’s plug-and-produce skids are designed for multi-product pharmaceutical and biopharmaceutical separation.

GoSilico’s software for digital twins of downstream biopharmaceutical processes will be integrated into Cytiva.

Sartorius has expanded in the United Kingdom with the relocation to a new facility in Havant, Hampshire, for downstream processing equipment.

The need for real-time monitoring and control has spurred the development of new analytical tools.

The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.

Synthetic depth filters are a suitable option to provide a high-performance and scalable single-step clarification process.

Sartorius adds chromatography systems and resins, tangential flow filtration, and biomolecular characterization technologies.

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost.

GEA began supplying the new GEA Hilge Novatwin hygienic twin-screw pump line.

The need for manufacturing speed inspires contract manufacturers to explore advanced processing technologies.

The freedom of design found in additive manufacturing offers the potential for improved processing equipment, both in prototypes and commercial equipment.

The $10-million investment will include a 500-L single-use perfusion bioreactor and seven patented downstream processing units.

Large biopharmas, emerging biotechs, and CMOs are looking for novel ways to improve the productivity of biologics in a rapidly evolving biotherapeutics market.

Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.

The company’s Quantum peristaltic pump uses a patented single-use cartridge technology and is applicable to downstream bioprocessing.

The BioContinuum Buffer Delivery Platform offers streamlined buffer management and delivers “contiGuous” bioprocessing.

Pharmaceutical Technology and BioPharm International will present a Keynote Session on Meeting Bioprocessing Manufacturing Capacity Demands on Wednesday, April 3, 2019, during INTERPHEX 2019 at the Javits Center in New York City.

Laboratory test methods evaluate cleaning agents and cleaning process design for removing resin residues from the surfaces of non-dedicated chromatography columns systems.

Sartorius Stedim Biotech (SSB) and Novasep will partner to develop systems for membrane chromatography using Novasep’s BioSC platform and SSB’s single-use technology.