Aseptic Micro-Connector

The MicroCNX ULT Series from Colder Products Company (CPC) is the first aseptic micro-connector that can be fitted directly into freeze cassettes used in cell and gene therapy (CGT) processing. It can be frozen to -190 °C. It is compatible with the most common types of tubing, including polyvinyl chloride (PVC), used in developing advanced therapies. The connectors are compact enough to fit into a freeze cassette and can be frozen with vaporized liquid nitrogen. They are designed to provide a simple, efficient method of sterile connection of tubing used for small CGT assemblies. They also eliminate the need for adding extra tubing into the process, thus helping to reduce the amount of product hold-up or product loss. The MicroCNX ULT series termination and flow path are constructed from polyphenylsulfone, a high-performance polymer that is chemically compatible with the harsh chemicals, such as dimethyl sulfoxide, used in cryopreservation processes. This new series adds to CPC’s 1/8” MicroCNX Series Connectors, an alternative to tube welding in creating closed sterile connections at small volumes. Similar to earlier MicroCNX products, the MicroCNX ULT series features a 1/8” flow path and offers options for 1/8”, 3/32”, and 1/16” hose barb terminations to support a variety of tubing sizes and materials, such as PVC, silicone, and thermoplastic elastomer.

CPC