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June 09, 2005
Self-Assembly Nanotechnology Improves Microencapsulation
June 02, 2005
Once considered mainly an afterthought in a company's lifecycle-management strategy, controlled-release dosage forms are now positioned at the forefront of many formulation strategies. In contrast to drug discovery, formulation work focuses not only on the intricacies of the active pharmaceutical ingredient (API), but also on fine-tuning the excipients, the release profile, and the delivery mechanism to provide optimal therapeutic benefit. Because of their wide range of applications and functionalities, especially in controlled-release therapies, polymers are among the most widely used excipients.
Wet granulation is a size-enlargement process in which a liquid is used to achieve the agglomeration of solid particles. Agglomeration improves particles' tableting properties by rendering them free-flowing, nonsegregating, and suitable for compression (1).
June 01, 2005
HR-US is a nondestructive technique with enormous potential for the analysis of materials and formulations used in the pharmaceutical industry.
This high quality of pellet roundness is surprising in view of the high extrusion forces required to extrude the wet masses.
May 27, 2005
New Excipient Guidance Doesn?t Fill Regulatory Gap
May 26, 2005
It Helps to be Flexible: Supple WIN Compounds Could Cure the Common Cold
May 19, 2005
Cytogen and Dowpharm to Develop Targeted Anticancer Product
May 02, 2005
Vaccine developers are using novel drug delivery methods that offer advantages over traditional techniques such as improved immunogenicity, better stability, specific control over antigen release, and a wider pool of targeted diseases.
Vaccine developers are wrking on new drug delivery systems that offer improved immune responses, better stability, and a wider pool of targeted diseases.