Jonathon Salsbury is an associate director at PPD GMP Lab, Middleton, WI.
The Impact of Vortexing on the Particle-Size Distribution of Pharmaceuticals
November 15th 2018If a vortex mixer produces too much energy during sample preparation for particle size analysis, the size and morphology of particles can change. A study compares the applied shear to sample suspensions of ibuprofen to observe the effects of applied shear on the particle size distribution.