Manufacturing

Adherence to detail and thorough project management are required for successful tech transfer and scale up.

Replacing a step in sample preparation with an automated approach improves both method precision and productivity.

In this article, the potential pitfalls of technology transfers are discussed as well as ways to ensure a smooth transition.

Gerresheimer and Nelson Labs will work together to conduct extractables and leachables testing on upcoming primary packaging solutions.

Pharma companies set goals and adopt more sustainable alternatives.

Steriline will be exhibiting its vial filling and capping machine (VFCM100) under double-wall isolator for aseptic filling at CPHI 2022 in Frankfurt, Germany, on Nov. 1–3, 2022.

The ROSS VersaMix Multi-Shaft Mixers are designed for processing medium-to-high viscosity applications up to several hundred thousand centipoise.

HeliFlex from Freudenberg Medical is a high purity TPE designed for biopharmaceutical fluid transfer applications.

Akadeum’s Life Sciences isolation kit uses microbubbles to reduce leukopak production time.

Evoqua’s Sophis digital services is a holistic monitoring and analysis solution for pharmaceutical water management.

In this episode, Alivia Leon, assistant editor, speaks with Christian Dunne, director of global corporate business development, Chargepoint Technology, about current and future processing equipment trends, such as automation, cost, and sustainability.

The newly formed partnership between CSafe and BioLife will expand cold chain supply chain solutions for the cell and gene therapy market.

Cambrex has expanded its stability storage business, Q1 Scientific, in Ireland and Belgium.

Vibha Jawa, executive director at Bristol Myers Squibb, and Luke Schenck, principal scientist at Merck & Com, discuss cell & gene therapies and co-processed APIs respectively.

Under two new agreements, Societal CDMO will offer analytical, technical transfer, formulation, manufacturing, and packaging services for novel therapeutics.

Pharma supply chains are no longer hidden beyond the reach of ESG agendas, making it important for companies to accelerate adoption of new manufacturing processes and environmental technology

Aragen’s new 12,000 ft² facility will include various dosage form capabilities, including oral solids, liquids, topicals, and films.

Recipharm’s new high speed filling line, designed for pre-filled syringes and cartridges, is expected to be operational by May 2023.

Product safety and security are paramount when it comes to container closures.

Significant improvements have been developed to tackle the challenges in viral vector manufacturing at each stage.

The authors discuss the differences in mechanism of activation of N-nitrosamides versus N-nitrosamines and the fact that they should not be treated the same.

Cytiva’s acquisition of CEVEC Pharmaceuticals strengthens the company’s cell line development and biomanufacturing capabilities.

Thermo Fisher’s new centrifuge technology is designed to enable efficient, sustainable cell culture harvesting.

Freudenberg Medical’s Heflix TPE tubing is a high purity TPE intended for bioprocessing applications.

Recent technological advancements may have put cleanroom monitoring into a state of flux.

Production of viral vectors requires a holistic view of the product, including its manufacturing process and its ultimate end use.

Experts outline the benefits of single-use consumables relative to traditional approaches.

External expertise is beneficial in helping companies select the right tools at the right stages of development to ensure success.

Standardized risk assessment and analysis protocols facilitate the comparison of processing equipment components.

BFS technology can help maintain sterility during the biologics manufacturing process.