Manufacturing, Separation and Purification

Purolite and Repligen have commercially launched a new CH1 affinity resin for the purification of specialized mAbs.

The services are based on the company’s PurePrep EasyClean (PEC) orthogonal peptide purification technology.

Sartorius BIA Separations and Teknova will collaborate to combine their technologies in an effort to streamline the downstream purification process.

The R&D analytical solutions will consist of analytical lab services that use USP’s in-house scientific expertise and state-of-the-art facilities at the USP Advanced Manufacturing Technology Lab in Richmond and the USP headquarters facility in Rockville, Md.

The $19 million contract will expand production capacity of Aptar’s Activ-Film technology, which is used in COVID-19 testing kits.

The 3M Harvest RC clarifier condenses three process steps into a single-stage purification of recombinant protein therapeutics.

Sartorius has expanded in the United Kingdom with the relocation to a new facility in Havant, Hampshire, for downstream processing equipment.

The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.

The 6th-generation Eclipse FFF system handles analytes such as proteins, polymers, viruses, gene vectors, and liposomal drug nanoparticles.

Synthetic depth filters are a suitable option to provide a high-performance and scalable single-step clarification process.

Bioprocessing advances improve product yield, cut costs, and streamline integration between upstream and downstream processes.

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost.

The companies will focus on identifying peptides applicable to the affinity chromatography process used in the purification of biopharmaceuticals.

The new program, Cornerstone, integrates process development expertise and novel technology to remove development bottlenecks in the manufacture of gene therapy medicinal products.

Knauer has introduced new columns and screening services for the enantioseparation of chiral substances.

Large biopharmas, emerging biotechs, and CMOs are looking for novel ways to improve the productivity of biologics in a rapidly evolving biotherapeutics market.

The company’s Quantum peristaltic pump uses a patented single-use cartridge technology and is applicable to downstream bioprocessing.

Pharmaceutical Technology and BioPharm International will present a Keynote Session on Meeting Bioprocessing Manufacturing Capacity Demands on Wednesday, April 3, 2019, during INTERPHEX 2019 at the Javits Center in New York City.

Laboratory test methods evaluate cleaning agents and cleaning process design for removing resin residues from the surfaces of non-dedicated chromatography columns systems.

The VMC VersaMix by Charles Ross & Son Company is suited for temperature-critical formulations of medium to high viscosity under stringent vacuum/pressure constraints.

Requirements for virus filtration must be considered in developing continuous downstream processes.

The investment builds on a collaboration the companies entered into in 2007 for various biomanufacturing projects.

GE’s new facility, which will be operational in 2019, will produce a fiber-based chromatography platform for more efficient biopharmaceutical purification.

The new features on the purifier deliver additional sizes and sterilization/sanitization compatibility.

The media, by Tosoh Bioscience, is composed of calcium and phosphate buffers and offers mixed-mode properties for biomolecule purification.

The new resin used a combination of “jetting” technology and a high-performance Protein A ligand.

The company’s next-generation ultraperformance liquid chromatography platform is designed to meet the evolving laboratory requirements for chromatographic performance.

CoorsTek will highlight two new ceramic membrane filter technologies at the show-the multi-tube system, which consists of four single ceramic tubes connected together into a single ceramic part, and the hollow fiber system, which consists of ceramic tubes assembled into a high-density module.

The new Acquity Arc Bio System by Waters is specifically engineered to enable efficient transfer and improvement of bioseparation analytical methods.

The acquisition gives GE Healthcare access to a nanofiber-based platform purification technology that can offer improvements in biopharmaceutical productivity.