Equipment

Early planning for the integration of clean-in-place systems for equipment cleaning is key.

Pfizer broke ground at its Andover, Massachusetts campus on a clinical manufacturing facility for complex biologics and vaccines.

The company will be exhibiting at the 2016 International Fuel Ethanol Workshop and Expo.

Alvotech prepares for commercial biosimilar production in new facility with single-use bioreactors in Reykjavik, Iceland.

Customized puresu single-use fluid path assemblies from Watson-Marlow Fluid Technology Group incorporate tubing and BioPure components and are supplied ready to use.

Preheating pinch valves prevents drift in the volume of liquid dispensed.

Industry experts discuss common considerations and recent technological advancements in blow-fill-seal technology.

Packaging technologies for serialization, parenteral products, and solid-dosage forms were displayed at INTERPHEX 2016.

In this article, the authors look at the limitations of the validation for a single-use shipping system and provide a perspective on what shipping validation means.

Fogg Filler’s enclosures for bottle-rinsing machines have improved fume containment and doors with lift-off hinges for maintenance.

MilliporeSigma expands its Carlsbad, California-based GMP capacity for viral and gene-therapy products by nearly 90%.

MilliporeSigma, the North American life-sciences business of Germany’s Merck KGaA, added a 2000-L single-use bioreactor to its facility in Massachusetts.

The company announced the launch of its first-in-class Lynx CDR connectors at INTERPHEX 2016.

The Spark 20M multimode microplate reader has the ability to read 6- to 1536-well microplates and includes a high-frequency xenon flash lamp that can be combined with detection modules.

The Dionex Integrion High-Pressure Ion Chromatography system from Thermo Scientific includes high-pressure capability and electrochemical detection.

The Zeiss Smartproof 5 wide-field confocal microscope is designed for applications in quality assurance and quality control, production, and R&D laboratories.

The IH-TMS Tool Management System from I Holland monitors tool rotations, tooling inventory, and maintenance.

The advanced capillary electrophoresis system, Maurice, from ProteinSimple is used for the quantitative analysis of identity, purity, and heterogeneity profiles of biopharmaceuticals.

High Speed Dispersers from Ross feature a National Electrical Manufacturers Association (NEMA) 7&9 Operator Panel and grounding systems.

The Class 100 cleanroom oven from Grieve is used for a variety of heat processes such as sterilizing, depyrogenation, curing, and drying workloads.

The authors provide their perspectives on shipping validation.

Tablet presses require regular inspection and maintenance to prevent premature wear and tableting problems.

National Bulk Equipment’s material handling system for non-free flowing materials can be specified to meet cGMP cleanability standards.

Manufacturing of antibody drug conjugates requires high-containment solutions, such as high-performance aseptic isolators.

When implementing disposable technology for aseptic processing, considerations include material compatibility, material sourcing, facility layout, and training.

The Alfa Laval Safety Valve, a true spring-loaded safety valve, is designed to protect both equipment and people.

Collaboration between users and suppliers to increase understanding, clearly define user requirements, and mitigate risk is facilitating acceptance by industry and regulators.

Millipore Express PHF hydrophilic, sterilizing-grade filters from EMD Millipore offer faster flow rates to speed the process or reduce the process footprint.

Grand River Aseptic Manufacturing expands disposable technology capabilities at aseptic facility.