In the Spotlight November 2010
Editors' picks of pharmaceutical science and technology innovations.
Formulation Development Forum: Abuse-deterrent combination drugs
Abuse-deterrent combination drugs represent a niche area in formulation development.
Inside USP: Adulteration and Contamination Awareness
USP is working to ensure quality standards and to increase public information.
Keep It Clean
A recent book offers an excellent overview of cleaning validation.
Report from India
IP rights and levels of innovation have opened a bit of controversy regarding decisions being made by Indian courts and legislators.
Solubilizing the Insoluble
An analysis of the approaches and tools used to tackle the problem of poorly soluble drugs.
Advances in Solid-State Chemistry
Industrial and academic partnerships forge new territory in solid-state chemistry.
Automated Inspection of Pharmaceutical Products
A conversation with Mike de la Montaigne, president of Eisai Machinery, USA Inc., about the possibilities for conducting fully automated product inspections.
Ideas Know No Borders
As technology advances, industry's needs are growing.
A Common Future Requires Collaboration
Scientists and practitioners must work together for the overall good of the patient.
Comparative Research Poses Challenges
A new center may provide evidence for improving care, but could discourage coverage of treatments.
A Proposed Content-Uniformity Test for Large Sample Sizes
The authors describe a modified version of the Large-N test used to determine content uniformity.
China's State Food and Drug Administration Discusses Drug Applications
A Q&A with officers of the departments of State Food and Drug Administration, China, moderated by Ji Xie.
Development of an Osmotically Controlled Drug-Delivery System of Glipizide
The authors describe the development of an inclusion complex of GLZ and formulated an extended-release dosage form based on osmotic technology.
Insider Solutions Rule #1: Be in Compliance
Drug manufacturers have to be more than just "audit ready."
Balancing Act
Remaining calm, cool, and collected during mergers and inspections is a feat in itself.
Method Development for Laser-Diffraction Particle-Size Analysis
The author examines the process of method development, with reference to ISO 13320:2009 and relevant monographs from the United States and European pharmacopoeias.
In Vivo Evaluation Using Gamma Scintigraphy
The authors discuss gamma scintigraphy as a technique for in vivo evaluation of drugs and delivery systems.
Orally Disintegrating Tablets Using Starch and Fructose
The authors demonstrated that ODTs can be obtained by direct compression of a mixture of starch, fructose, and SMCC.
Global Healthcare on the Ground: Merck and AstraZeneca Tackle Cervical Cancer and Tuberculosis
Merck and AstraZeneca Tackle Cervical Cancer and Tuberculosis.
Outsourcing Winners in 2014
Post recession and beyond, which contract service providers will still be standing?
Innovation In Depth
Connecting science and policy might increase support for innovation.
Used Is the New "New"
Used packaging equipment can be a cost-saving, time-saving alternative to new machines.
Solutol HS15 as a Novel Excipient
The authors present an update to the Wyeth/BASF experience with the IPEC Novel Excipient Safety Evaluation Procedure.
Q&A with Stuart Needleman, Aptuit
Stuart Needleman, president of active-ingredient development and manufacturing at Aptuit, discusses industry trends and challenges.
Walk Like a Statistician
Applied statisticians are forever searching for the enemy of quality-variability.
Pharmaceutical Technology, November 2010 Issue (PDF)
