Process Engineer at Boehringer Ingelheim Pharma GmbH & Co KG
Filling of Asthma Inhalers with Liquid Nitrogen: Cryogenic Product Cooling of Aerosol Propellants
October 1st 2003This case study describes how a major pharmaceutical manufacturer was equipped with four filling lines, for metered dose inhalers, supplied with a nitrogen cooling system to prevent spontaneous vaporization of the propellant gas. By doing so, a cost-effective and environmentally friendly solution was provided to a hazardous situation, which also complied with regulatory directives.