Navnit H. Shah is a distinguished research leader, all at the pharmaceutical and analytical research and development department of HoffmanâLa Roche Inc. (Nutley, NJ).
Effect of Formulation and Process Variables on Matrix Erosion and Drug Release from a Multiunit Erosion Matrix of a Poorly Soluble Drug
By optimizing formulation and process varibles, pellets can be prepared that can release a poorly soluble drug for 12-24 h following zero-order kinetics.