M. Serpil Kislalioglu, PhD, is a professor of pharmaceutics at the Department of Applied Pharmaceutical Sciences, College of Pharmacy, The University of Rhode Island, Kingston, RI 02881, tel. 401.874.5017, fax 401.874.2181.
Effect of Formulation and Process Variables on Matrix Erosion and Drug Release from a Multiunit Erosion Matrix of a Poorly Soluble Drug
By optimizing formulation and process varibles, pellets can be prepared that can release a poorly soluble drug for 12-24 h following zero-order kinetics.