Christopher L. Franklin is a research investigators, at Millennium Pharmaceuticals, Inc., 40 Landsdowne St., Cambridge, MA 02144, USA.
A New Approach to Forced Degradation Studies Using Anhydrous Conditions
March 2nd 2014In this article, the authors demonstrate that a normal-phase chromatographic method was stability-indicating for a water-sensitive prodrug. The stress conditions using aqueous and non-aqueous conditions were also compared to understand the information obtained with each approach.