Christopher Burgess, PhD, is managing director, Burgess Analytical Consultancy Limited, Barnard Castle, Co Durham, UK.
Never Mind the Statistics; Just Tell Me What the Answer Is!
How confident are you in your lab results? This paper explores this question and, by way of a worked example, provides a methodology to answer it.
Weighing Isn’t an Uncertain Process, Is It?
This article provides best practice to avoid errors in weighing by difference caused by buoyancy and drift.
Detecting and Determining Quantitation Limits for Impurities
Different methods give different answers when calculating limits for impurities. The prediction interval method may be the best option.
Distribution of Data: The Central Limit Theorem
Using the central limit theorem concerning the distribution of means allows one to justify the assumption of the normal distribution.
Process Stability, Performance, and Capability; What is the Difference?
This article applies the basics of stability, performance, and capability to modern process performance and capability indices.
Singlet Determination Revisited
Is there a difference between a specification and a standard?
For Lab Equipment Qualification, Data Reveal Important Story
A case study presents important lessons for using average and individual results, as well as user requirements, when qualifying a laboratory refrigerator.
Do You Listen to What Your Data are Telling You?
This column presents a data case study of a laboratory refrigerator and its qualification performance over five days, with important lessons for using average and individual results, as well as user requirements.
Demonstrating a State of Control
Do you have acceptable control of your instruments and analytical procedures?
Is Your Calibration Really a Good Straight Line?
Statistical procedures give statistical answers not analytical judgement.
How Accurate are Your Dilutions?
The choice of dilution schemes can minimize solution preparation errors.
Is a Sample Size of n=6 a 'Magic' Number?
Statistical analysis shows how much testing is needed to deliver a reliable estimate result.