Sterilization Effects on Elastomers in Sterile Parenteral Drug Products

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Pharmaceutical TechnologyPharmaceutical Technology-05-15-2015
Volume 2015 eBook
Issue 2

This article looks at data gathered from several studies of a widely marketed chlorobutyl rubber formulation used for vial stoppers and prefilled syringes.

 

This article looks at data gathered from several studies of a widely marketed chlorobutyl rubber formulation used for vial stoppers and prefilled syringes. The studies examined material properties, machinability, function in syringes, and extractables, comparing the use of these sterilization techniques on rubber slabs and prefillable syringe plungers. 

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Articles in this issue
PTeBook0515_024-030_Container200.jpg
Sterilization Effects on Elastomers in Sterile Parenteral Drug Products
PTebook0515_Linde200.jpg
Controlled Nucleation for a Monoclonal Antibody Formulation—A Case Study
PTeBook0515_EMDConfarma200.jpg
Validating and Implementing a Rapid Sterility Testing Method
PTeBook0515_Vetter200.jpg
Disposable Technology versus Traditional Stainless Steel--When Time Means Money
PTeBook0515_Cleanroom200.jpg
Cleanroom and Facility Planning: Getting Beyond Cost Per Square Foot
PTeBook0515_Aging_Facilities200.jpg
Aging Facilities: Aseptic Manufacturing Faces the Future
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