Single-Use Systems Expand Scale of Chromatography
Sartorius Stedim Biotech has expanded its range of single-use membrane chromatography solutions with Sartobind Cassettes, a pod-like modular system for commercial applications in both capture and polishing.
Sartorius Stedim Biotech has expanded its range of single-use membrane chromatography solutions with Sartobind Cassettes, a pod-like modular system for commercial applications in both capture and polishing. The cassettes offer the same flow path, bed heights (4 and 8 mm), and void volume ratios as Sartobind capsules, and are compatible with quaternary ammonium (Q), sulfonic acid (S), salt-tolerant interaction chromatography primary amine (STIC PA), and phenyl ligands. The new design goes beyond the previous 5-L size limitation for capsule formats, expanding the boundaries of membrane chromatography. Multiple cassettes, each with 0.8-L or 1.6-L membrane volume, can be set up in three different stainless-steel holders, resulting in maximum membrane volumes of 20, 50, or 100 L, respectively. Pressure-flow performance and the shape of breakthrough curves are identical to the smaller capsule sizes, independent of the number of cassettes used. Set up can be accomplished within minutes, even at manufacturing scale.
Sartorius Stedim Biotech
Drug Solutions Podcast: Applying Appropriate Analytics to Drug Development
March 26th 2024In this episode of the Drug Solutions Podcast, Jan Bekker, Vice President of Business Development, Commercial and Technical Operations at BioCina, discusses the latest analytical tools and their applications in the drug development market.
Legal and Regulatory Perspectives on 3D Printing: Drug Compounding Applications
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