Sartorius Introduces New TFF Cassette that Offers Streamlined Workflow in the Lab

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Editor's note: this story was originally published on BioPharmInternational.com.

On Sept. 9, 2024, Sartorius announced the launch of its Vivaflow SU tangential flow filtration (TFF) cassette. The Vivaflow SU is designed to be more user-friendly and to allow for more flexibility in laboratory workflows. The new cassette offers more efficient and sustainable ultrafiltration and diafiltration processes for feed volumes in the range of 100 mL–1000 mL.

According to a company press release, the new all-in-one cassette reduces cost and complexity and streamlines workflows for molecule isolation in a sustainable manner. Each cassette is ready to use and has a standard laboratory pump, which enables simple set-up. The simplified set-up avoids the need for expensive systems and expensive process optimization and allows for faster and more reliable concentration and rebuffering of any molecule. The cassette also eliminates the need for cleaning and reduces contamination risk while minimizing waste, according to the press release.

“Vivaflow SU is a testament to our promise to always simplify progress,” said John Cashman, product manager for Lab Ultrafiltration at Sartorius, in the press release. “It takes the ease-of-use that our customers already value about TFF with Vivaflow and elevates the experience with improved handling and performance, while reducing waste. Our next-generation cassette eliminates the need for feed flow rate, TMP [transmembrane pressure], and permeate flux calculations, while also offering sustainability improvements that are truly impressive for a single-use consumable.”

Sustainability features of the new cassette include a new housing that uses 30.5% less plastic. It also incorporates several eco-friendly design improvements, such as locally sourced raw materials, customized tubing kits for each cassette configuration, a digital user manual, and reduced non-recyclable packaging; all these design elements contribute to a lower research footprint, the company stated in the press release.

Vivaflow SU is the-next-generation TFF cassette that replaces the previous Vivaflow 50. It is meant for research scientists who require a fast and reliable means for concentrating and rebuffering large feed volumes in molecule isolation workflows.

The launch of Vivaflow SU follows on the heels of Sartorius’ earlier launch of the Arium Mini Extend water purification system for laboratories in June 2024 (1). The Arium Mini Extend is the newest member of the Arium Mini product line. The new purification system is designed to meet the Type 1 water demands of laboratories for general, life-science, and analytical applications, according to the company in a press release. The new system is compact and offers ultrapure water purification with flexibility and convenience.

The new system comprises a flexible, ergonomic handheld dispenser, a user-friendly digital display, and the Arium Bagtank technology to significantly optimize laboratory workflows. The dispensing unit is equipped with an independent volume control function and expands the access area for ultrapure water. The new system streamlines water purification processes, especially those processes that require repeated dispensing. Meanwhile, operation and maintenance have been made simpler with intuitive menus and a 5-L Bagtank for storage of purified water. These features facilitate cleaning procedures and ensure uninterrupted laboratory workflows, the company stated in its press release.

Reference

1. Sartorius. Sartorius Launches New Arium Mini Extend with Flexible Arm for Versatile Type 1 Water Dispensing. Press Release. June 17, 2024.

Source: Sartorius