Mass Spectrometry System Standardizes Workflows

Publication
Article
Pharmaceutical TechnologyPharmaceutical Technology-04-02-2017
Volume 41
Issue 4
Pages: 13

The X500B QTOF System is the latest solution in SCIEX’s X-Series Quadrupole Time of Flight (QTOF) mass spectrometry (MS) platform.

The X500B QTOF System is the latest solution in SCIEX’s X-Series Quadrupole Time of Flight (QTOF) mass spectrometry (MS) platform. The system was specifically developed to deliver high-resolution standardized workflows for biotherapeutic developers, who are required to fully characterize biologic products in large numbers during the development process.

The X500B QTOF System comes with BioPharmaView Software 2.0, which offers the ability to interpret SWATH 2.0 data independent acquisition on the X500B QTOF System. SWATH acquisition allows for comprehensive peptide mapping data to be acquired in an injection, with high-resolution mass spectrometry and tandem mass spectrometry data for every peptide in the sample. This strategy results in the ability to detect low-abundance peptides and post-translational modifications. 

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