Equipment and Processing Report
PharmTech's monthly newsletter, Equipment and Processing Report, reviews the Editor's Picks for the February 2011 edition from Emerson Process Management and Spirax Sarco.
Emerson Process Management
Filling transmitter increases accuracy
Emerson Process Management’s Micro Motion filling-mass transmitter uses Multivariable Digital technology and a Coriolis sensor to perform high-speed, accurate filling. The device can accommodate fills that last less than 1 s and challenging fluids, such as those with entrained air, suspended solids, or high viscosity. The unit’s integrated valve control is designed to reduce external processing and increase accuracy. The transmitter is suitable for various linear and rotary filling machines in the life-sciences industry.
The Filling Mass Transmitter delivers mass, density, and temperature process data, thus supporting continuous monitoring of product quality with a real-time view of fluid characteristics. The unit’s digital communications capability enables real-time quality control and on-the-spot changes to fill targets or recipes.
In addition, the transmitter’s automatic overshoot compensation adjusts valves in response to changes in process conditions (e.g., delivery pressure and fluid characteristics). This feature enhances the unit’s accuracy and reliability and reduces setup and maintenance requirements.
Spirax Sarco
Sanitary valve prevents cross contamination
Spirax Sarco’s CVS10 sanitary check valve is designed to open when media exerts pressure on it. The valve has an internal spring-cracking pressure of 0.507 psi, and when media stops flowing, the spring’s force closes the valve before reverse flow and cross contamination can occur. The valve helps protect equipment from pressure surges associated with hydraulic forces, such as waterhammer. In addition, the device has a high flow coefficient and causes minimal pressure loss.
The CVS10 valve is available with a metal seat for clean- and pure-steam or condensate applications. A soft-seat version also is available for high-purity water and liquid applications, such as water-for-injection systems. All wetted materials throughout the valve are fully traceable.
In addition, clients can choose from various surface finishes, including a finish as low as 15 microinch Ra electropolished. Low surface finishes help to maintain sterility in the system by reducing the risk of microbial growth in crevices on the valve’s surface.
Drug Solutions Podcast: Applying Appropriate Analytics to Drug Development
March 26th 2024In this episode of the Drug Solutions Podcast, Jan Bekker, Vice President of Business Development, Commercial and Technical Operations at BioCina, discusses the latest analytical tools and their applications in the drug development market.