Gateway 2012: Cambridge Major Laboratories

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CAMBRIDGE MAJOR LABORATORIES – CRYSTALLIZATION AND SOLID STATE CHEMISTRY SERVICES

Cambridge Major Laboratories (CML) has established a new Center of Excellence for Crystallization and Solid State Chemistry in our Active Pharmaceutical Ingredient (API) development facilities in the Netherlands. Significant investments have been made in equipment and personnel as part of CML’s expansion into solid state services.

CML'S Solid State Chemistry Services

  • Crystallization Study – crystallize to obtain stable solids, for purification or isolation

  • Material Characterization – polymorph identification

  • Solubility Determination – in production solvents and buffer solutions

  • Salt Selection – suitable form selection

  • Polymorph Study – behavior in production solvents

  • Crystallization Process Development – combine optimal synthesis conditions with optimal crystallization conditions

  • Crystal Habit Optimization – control of particle size and shape

CML Overview

Analytical Services

API Manufacturing

Process Chemistry

Quality Assurance

Solid State Chemistry

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