CordenPharma to Expand Lipid Purification Capacity at its Colorado Site

CordenPharma announced on April 19, 2021 that it is expanding its lipid purification capacity at its Colorado site.

According to a CordenPharma press release, the expansion will include the addition of new production lines, which will be merged into the lipid manufacturing process in April 2021. By July 2021, the company expects a decrease in lipid shipment delivery time due to the expansion.

“CordenPharma is proud to contribute this major capital expansion to increase important lipid production for the global market,” said Michael Quirmbach, CEO and president, CordenPharma. “We have drawn upon longstanding expertise in specialized lipids to create an even stronger integrated network of facilities to support current and future projects.”

The company, who has also expanded its lipid supply chain at its facilities in Switzerland and France, manufactures four lipids used to formulate messenger RNA (mRNA)-based vaccines. They include:

• Cationic lipids that condense negatively charged mRNA
• PEGylated lipids that form a protective hydrophilic layer, which sterically stabilizes the lipid nanoparticle (LNP)
• DiStearoylphosPhatidylCholine (DSPC), a phospholipid that offers a stable bilayer-forming structure
• Plant-based cholesterol (CP BotaniChol), which stabilizes the LNP structures and enables endosome escape.

Source: CordenPharma