With the innovative and patented Bohle Uni Cone BUC® process a complete fluidization is assured which leads to a high coating uniformities and high yields in the final product.
L.B. Bohle developed the Bohle Fluid Bed Systems with tangentially mounted spray nozzles and the Bohle Uni Cone BUC®. This equipment is available for batch sizes ranging from 1 to 500 kg.
With the innovative and patented Bohle Uni Cone BUC® process a complete fluidization is assured which leads to a high coating uniformities and high yields in the final product due to the absence if particle twinning. Bohle Uni Cone BUC ® is the productive, practical and precise alternative to conventional Wurster processing.
By design all size fluid beds are geometrically similar which enables an easy scale up procedure. Dust free suction and discharge of the product bowl is performed through the use of a newly developed patented multi-functional valve directly above the distributer plate. The overall design of the BFS types results in substantial ergonomic benefits, which means major advantages in cleanability and processing in comparison to other existing fluid bed systems on the market. In addition, the low position of the valve allows easy operator access. Bohle Fluid Bed Systems contain fewer gaskets, valves and vents, which makes cleaning fast and easy.
All Bohle systems utilize a very efficient use of space.
Contact Details:
Tobias Borgers
Phone
: +49 (0) 2524 9323 150
Fax
: +49 (0) 2524 9323 399
Website:www.lbbohle.com
Diving Deep into Carrier-Based Formulation and Process Optimization
December 23rd 2024Carrier-based formulations for dry powder inhalers are carefully designed to transport extremely small particles into the lungs. Jet milling can be used to micronize these particles, with both high and low shear mixing processes used to formulate mixtures capable of carrying the fine API particles into the deep lung. This paper looks at the requirements for pulmonary delivery via carrier-based inhaled powder formulations, and how jet milling can be used to manufacture effective and stable materials for these formulations