Precise Control with Improved Drug Delivery
In pharma delivery, size matters. So, too, do the intricacies of dosage format, active ingredient compatibility, and effective delivery to patients—whatever their needs or preferences may be. Yet standard dosage forms haven’t always provided companies the options, flexibility, or performance to bring all those puzzle pieces together during therapeutic development. We spoke with Nathan H. Dormer, PhD, Director of Drug Product Development at Adare Pharma Solutions, to learn how this new technology platform is expanding the frontiers of therapeutic delivery and improving patients’ experience in the process.
Molecular Properties of PROTACs and the Relationship to Formulation Design
December 20th 2024Analyzation of a diverse set of PROTAC (Proteolysis Targeting Chimeras – a class of TPDs) structures and their calculated properties, identifying key structure-property trends that contribute to low oral bioavailability.
Clinical Supply Planning in Europe - Balancing Cost, Flexibility and Time
December 19th 2024The packaging and distribution of clinical supplies is a fundamental piece to the overall success of a clinical trial, and advance preparation can help establish a more efficient supply chain. Selecting the best geographical location for those activities, however, depends on the clinical trial protocol, business decisions, and even the investigational medicinal product (IMP) being studied.
A Discussion: In Vitro Release Testing and Its Application and Use in Generic Topical
December 18th 2024Lucy Zhou, Skin Lab Manager, discusses the importance and applications for utilizing in vitro Release Testing during development of generic topical drug compounds. Lucy discusses how IVRT can play a critical role by saving cost and time during product development and the techniques and applications for using in vitro testing to achieve desired product outcomes.
