OR WAIT null SECS
July 01, 2002
Dynamic powder-sampling methods may be the best techniques for obtaining a representative sample for determining particle-size distribution.
April 02, 2002
Powdered self-emulsified dosage forms provide an attractive alternative to filled-capsule preparations, but the selection of a proper excipient is crucial.
March 01, 2002
Semisolid dosage forms are advantageous in terms of their easy application, rapid formulation, and ability to topically deliver a wide variety of drug molecules.
February 01, 2002
Low levels of some microorganisms that are present in oral solid dosage forms are unlikely to present a risk to patients. The amount of water activity in these products can help determine when microbiological testing should be conducted.
January 01, 2002
To achieve the maximum performance from a tablet press run, operators must learn to distinguish between machine-related issues and granulation-related issues.
October 01, 2001
Tablet manufacturers often overlook critical basic concepts or established practices. The author draws from his own experiences and discusses how solid dosage manufacturers can improve production and product quality by optimizing major unit operations.
The authors modified a three-layer press to operate a compression-coated tablet process that may offer several advantages over tradditional compression coating operations.
September 01, 2001
The author assesses the compressibility of Plasdone S- 630 copovidone-based tablet formulations using roller-compaction and direct-compression processes.
Both academia and industry have been encouraged to generate quick­dissolving dosage forms as the demand for fast­disintegrating tablets and capsules has steadily increased.
July 01, 2001
Appropriate sampling procedures, proper preparation, and correct instrumental parameters may yield differing, but correct, results.