Formulation

Nanotechnology is enabling enhanced bioavailability, improved stability, and targeted delivery of challenging APIs.

Excipients and new processing techniques can make a real difference in the development of highly potent therapies.

Exploration of various formulation techniques is vital to provide effective delivery of poorly soluble drugs.

Discussing the advantages, limitations, and recent advances of HME with experts from AbbVie.

Nanobiotix has launched Curadigm, a spinoff company that will specialize in developing a nanotechnology platform for healthcare applications.

A new partnership is aiming to advance the use of sublingual delivery technology for challenging drugs.

Medherant has announced that it is the recipient of a new £2-million (US$2.5-million) investment from Mercia Technologies.

StarTab from Colorcon was designed to ensure functionality and stability for direct compression tableting.

Leachable silicone oil may have an effect on large-molecule APIs, making it important to establish a robust analytical method to detect and quantify the substance.

Knowing the source and understanding the impact on CQAs is crucial to optimum drug formulation and processing.

Particle morphology of magnesium stearate, added as an anti-caking agent in a high water‑soluble drug substance, has an influence on the dissolution rate of compressed tablets.

Intertek has announced the expansion of its pharmaceutical services laboratory in Melbourn, near Cambridge, UK, through the acquisition of a new 20,000 sq. ft facility.

Patient-centric drug development is becoming more important in the bio/pharma industry.

Catalent invests $5 million in hot melt extrusion capabilities at Somerset, NJ facility.

3M Drug Delivery Systems UK organization has revealed that it is relocating its R&D team to the Charnwood Campus, which is an officially designated Life Sciences Opportunity Zone in Loughborough, United Kingdom

Characterizing particles and understanding bulk powder behavior is critical to get the best pharma product.

Intracellular strategies offer an effective alternative approach to deliver a range of therapeutic proteins.

Easier access to information, targeting smaller patient populations, and increased regulatory focus on patient outcomes are driving patient‑centric drug development.

Flexibility and well considered manufacturing approaches could help tablet manufacturers face the increasing pressure resulting from the shifting bio/pharma development landscape.

Market demand and regulatory guidance continues to promote improved medication design.

Catalent announces investment for its Zydis ODT technology, offering increased drug load and taste-masking capabilities.

Understanding the API, delivery mechanism, and excipient functionality is essential to solving drug solubility challenges.

As biologics continue to push boundaries, the industry needs to take a holistic approach to formulation to ensure success.

Harmonization of best practices and regulatory requirements will enable developers to find the best stability testing approach.

The technology uses a silica nanoparticle to deliver vaccines and cancer treatments.

The drug is approved in the United States specifically for treating acquired thrombotic thrombocytopenic purpura, a rare blood-clotting disorder.

The challenge of achieving sustained delivery of an active ingredient or nutrient can be achieved with extended-release formulations.

This injection formulation of USP-grade leucovorin calcium is now available in the United States.

This article demonstrates how qualitative physical attributes testing can be used to characterize soft gel capsule rupture/disintegration during rectal administration.

New approaches seek to address formulation and delivery challenges for these complex molecules.