Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Articles

This review article discusses orally disintegrating tablets and their manufacturing technologies, development issues, and future trends.

Orally Disintegrating Tablets

Although agitation improves drying efficiency and ensures uniformity of the final dry material, it can also affect the physical properties of the product as it dries. This study evaluates the effect of scale up and equipment selection on an active ingredient undergoing granulation during the drying process.

Scale Up of a Granulation Phenomenon

A fleet of pharmaceutical manufacturers have green lighted new bar coding and e-pedigree pilots using electronic barcodes. But is Industry ready for full-scale RFID?

Securing the Supply Chain With RFID

Pharmaceutical science and technology innovation

In the Spotlight-September 2005

Genecor Wins Vaccine-Development Contract

Genencor Wins Vaccine-Development Contract

FDA Proposes Question-Based-Review System for Generics

FDA Proposes Question-Based Review System for Generics

FDA Calls Chiron Facility Acceptable; GSK Gets Green Light For Flu Vaccine

New Guidance May Speed Generic Approvals

The tablet formation of six different carrageenans was analysed by 3D modelling, Heckel analysis, the pressure–time function and energy calculations. It was found that the fibres experienced plastic deformation, which was accompanied by a great deal of elasticity. Measurement of elastic recovery in dependence on maximum relative density and time showed that relaxation is completed a considerable amount of time after tabletting. Shrinking of the fibres occurred in parallel with elastic recovery as a result of the reorganization of the fibre structure. The tabletting behaviour of carrageenans makes them suitable for the soft tabletting of pressure sensitive materials.

Carrageenans: Analysis of Tablet Formation and Properties (Part II)

Jim Miller is president of PharmSource Information Services, Inc., and publisher of Bio/Pharmaceutical Outsourcing Report.

Contract manufacturers serving the biopharmaceutical market add capacity in a bet on renewed growth for biomanufacturing.