Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Articles

Chiron Withdraws Measles Vaccine

GSK Loses Bid to Block Generic "Flonase"

Development Begins on Mutated H5N1 Virus Vaccine

Vaccine Update: New Avian Strain, FDA Guidelines, and Clinical Funding

Novavax, Bharat Biotech Team for Pandemic Influenza Vaccine Development

Quantitative data from the literature show strong relationships among average particle size, powder densification, tensile strength, and hardness.

Effects of Initial Average Particle Size on Tableting: Evaluating Predictive Tools for Crystal Engineers and Formulators

Transdermal matrix-type patches of Nefopam hydrochloride with a combination of pressure-sensitive adhesives were developed. The polymeric composition provided a controlled and sustained release of the drug from the patches and demonstrated favorable physicochemical characteristics.

Nefopam Containing Transdermal-Matrix Patches Based on Pressure-Sensitive Adhesive Polymers

BMS Receives FDA Approval for Transdermal Antidepressant

Because of the growing popularity of single-use materials, the identification, characterization, and qualification of new materials used for disposable processes have become increasingly important for both regulatory and production purposes. This article describes one approach to identifying and validating the materials used in a disposable filling process.

Characterization, Qualification, and Validation of a Disposable Final Filling Process for Parenteral and Ophthalmic Drugs

GSK Gains Approval for Rotavirus Vaccine in Infants; FDA Review Extended for Merck’s Shingles Vaccine

GSK Gains Approval for Rotavirus Vaccine in Infants; FDA Review Extended for Merck's Shingles Vaccine

Human plasma provides a rich source of therapeutic medicines, including gamma globulins, coagulation factors, albumin, alpha anti-trypsin and others. In 2001, sales of immuno gamma-globulin (IgG) were estimated at $2 billion with a production rate of 50 metric tons for the year.1 A number of therapeutic products have been introduced including Gammimune from Bayer, RhoPhylac from ZLB Behring and Octagam from Octapharma.