Advancements in personalized medicine and other innovations are transforming the way dosage forms are viewed.

Reshaping Dosage Forms

This study aimed to develop a taste-masked drug resin complex using the ion exchange resin Kyron T-114.

Development of Taste-Masked Oral Dispersible Tablets of Cefpodoxime Proxetil

Novel genetic engineering technologies are transforming the design and manufacture of bispecific antibodies, which are emerging as a promising new class of biologics.

Frontrunners in Bispecific Antibodies

Topic

Articles

Scientists from GlycoFi, Inc., a wholly owned subsidiary of Merck & Co, in collaboration with Dartmouth-Hitchcock Medical Center, have engineered yeast cells capable of producing a broad range of recombinant therapeutic proteins with fully human sugar structures (glycosylation).

Re-engineered Yeast Glycosylation System Might Replace Mammalian Cell Expression

The overall market size of the Southeast Asia region totals $7 billion, with a projected compound annual growth rate of about 13% through 2010. 

Healthy Contrasts: A Look at Markets and Health Systems Across the ASEAN Region

For once, casting originators against generic players might end up strengthening the industry across the board.

Stage Fright: The Risks and Benefits of Moving Forward

As the pace of product development accelerates, the approach to dissolution-method development must advance beyond a manual method and an assay. A natural progression of the method-development process must include the transfer of the manual method onto automated instrumentation.

A Compliance Perspective on Dissolution Method Validation for Immediate-Release Solid Oral Dosage Forms on Automated Instrumentation

Patricia Van Arnum was executive editor of Pharmaceutical Technology.

Potent-compound awareness training for operators is important to understand why the containment and controls are in place. 

Contract Manufacturing Organizations Expand in High-Potency Manufacturing

Washington, DC (Aug. 14)?A new report issued by the Pharmaceutical Research and Manufacturers of America identifies 418 drugs and vaccines developed through biotechnology. All of the biotechnology medicines and vaccines are now in clinical trials or awaiting approval by the US Food and Drug Administration (Rockville, MD).

PhRMA Reports Identifies More than 400 Biotech Drugs in Development

West Point, PA (Jul. 31)?A survey of 150 US pharmacists found that nearly 80% believe that "multiple look-alike medications" make it difficult for consumers to identify the correct medication, especially when the drugs are moved to unlabeled containers.

Survey: Pharmacists Say Distinctive Tablets Reduce Dispensing Errors

Aegis Therapeutics (San Diego, CA) has launched a new formulation technology to increase the stability of proteins and peptides.

Formulation Technology Increases Protein Stability

GlaxoSmithKline (London, England) has developed a vaccine against the H5N1 bird flu strain that, the company says, shows better immune response than other vaccines in development.

GlaxoSmithKline Progresses on H5N1 Pandemic Flu Vaccine

Quantitative data from the literature show strong relationships among average particle size, powder densification, tensile strength, and hardness.