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Systematic Troubleshooting for LC/MS/MSMeeting the challenges of large-scale LC/MS/MS such as elminating carr-over and matrix effects can increase sensitivity and improve turnaround times.
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Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey ModelsThe delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.
Latest:
Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey ModelsThe delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.
Latest:
Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey ModelsThe delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.
Latest:
Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey ModelsThe delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.
Latest:
Oral Low Molecular Weight Heparin Absorption From Solution and Solid Dosage Forms in Rat, Dog, and Monkey ModelsThe delivery agent-mediated transport of low moleular weight heparin across Caco-2 cells is accomplished without opening the junctions or adversely affecting the structural integrity of the cell monolayer.
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Validation Changes to the USP Assay Method for Ibuprofen TabletsThis study investigated the effectiveness of the direct extraction of tablets and shaking time on the disintegration of tablets, solubilization, and recovery of ibuprofen from tablets of various formulations, strengths, and spiked placebo.
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Validation Changes to the USP Assay Method for Ibuprofen TabletsThis study investigated the effectiveness of the direct extraction of tablets and shaking time on the disintegration of tablets, solubilization, and recovery of ibuprofen from tablets of various formulations, strengths, and spiked placebo.
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Validation Changes to the USP Assay Method for Ibuprofen TabletsThis study investigated the effectiveness of the direct extraction of tablets and shaking time on the disintegration of tablets, solubilization, and recovery of ibuprofen from tablets of various formulations, strengths, and spiked placebo.
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Recent Advances in Semisolid Dosage Forms for Dermatological ApplicationSemisolid dosage forms are advantageous in terms of their easy application, rapid formulation, and ability to topically deliver a wide variety of drug molecules.
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Functionality Testing of a Multifunctional Directly Compressible Adjuvant Containing Lactose, Polyvinylpyrrolidone, and Croscarmellose SodiumThe authors review their study that aimed to develop a coprocessed, directly compressible, multipurpose adjuvant that could serve as a diluent and built-in disintegrant.
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The Usefulness of 0.45 µm–Rated Filter MembranesIn this study, the authors examine the suitability of 0.45 µm–rated filters to be used as sterilizing and bioburden-reduction filters against significant populations of organisms such as B. diminuta in a wide range of differential pressures.
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Effect of Extragranular Microcrystalline Cellulose on Compaction, Surface Roughness, and In Vitro Dissolution of a Self-Nanoemulsified Solid Dosage Form of UbiquinonePowdered self-emulsified dosage forms provide an attractive alternative to filled-capsule preparations, but the selection of a proper excipient is crucial.
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Effect of Extragranular Microcrystalline Cellulose on Compaction, Surface Roughness, and In Vitro Dissolution of a Self-Nanoemulsified Solid Dosage Form of UbiquinonePowdered self-emulsified dosage forms provide an attractive alternative to filled-capsule preparations, but the selection of a proper excipient is crucial.
Latest:
The Usefulness of 0.45 µm–Rated Filter MembranesIn this study, the authors examine the suitability of 0.45 µm–rated filters to be used as sterilizing and bioburden-reduction filters against significant populations of organisms such as B. diminuta in a wide range of differential pressures.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Oral Delivery of Macromolecular DrugsMacromolecular drugs are typically injected, but oral dosage forms are being developed to improve the treatment of gastrointestinal conditions such as inflammatory bowel disease.
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Application of API-in-Capsule Best Practices to Accelerate Drug Product DevelopmentAPI-in-capsule approaches enable pharmaceutical companies to quickly assess new drug candidates with reduced API consumption and to increase speed to clinic.
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Designing Combination ProductsAPI can be mixed with silicone and other polymers to create drug-delivery combination products.
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Designing Combination ProductsAPI can be mixed with silicone and other polymers to create drug-delivery combination products.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Alteration in Dissolution Characteristics of Gelatin-Containing Formulations: A Review of the Problem, Test Methods, and SolutionsEventual change in the dissolution characteristics of some dosage forms, which is ascribed to cross-linking of gelatin, continues to present challenges to drug manufacturers. The authors discuss the causes, mechanisms, and solutions to the problem.
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Monitoring Blend Uniformity with EffusivityBy moving uniformity monitoring back to the blender phase, blend variations that result from factors such as particle distribution and environmental temperature and humidity can be identified early.
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Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical ManufacturingThis article discusses the use of ion mobility spectrometry as an alternative to high-performance liquid chromatography to reduce the amount of time spent on the cleaning verification process.
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Using Ion Mobility Spectrometry for Cleaning Verification in Pharmaceutical ManufacturingThis article discusses the use of ion mobility spectrometry as an alternative to high-performance liquid chromatography to reduce the amount of time spent on the cleaning verification process.
