Implementing Continuous Bioprocessing: From Theory to Practice

Publication
Article
Pharmaceutical TechnologyPharmaceutical Technology, Trends in Manufacturing, May 2022
Volume 2022 eBook
Issue 2
Pages: 36–38

The struggle to implement continuous biomanufacturing at GMP level is slowly advancing.

Tashatuvango/Stock.adobe.com – The struggle to implement continuous biomanufacturing at GMP level is slowly advancing.

Tashatuvango/Stock.adobe.com

The evolution of technologies on the bioprocessing front is enabling an ability to perform continuous processing for biologic production. Although successes have been shown at small scale, challenges arise when translating continuous processes to large-scale good manufacturing practice (GMP) level. With the help of technological advances and innovative thinking, however, the potential to implement GMP-scale continuous bioprocessing is getting closer to reality. This article looks at real-world experiences of some companies that tested out the implementation of continuous manufacturing systems for GMP-scale biologics manufacture.

Read this article in Pharmaceutical Technology’s May 2022 Trends in Manufacturing eBook.

About the author

Feliza Mirasol is the science editor for Pharmaceutical Technology and Pharmaceutical Technology Europe.

Article Details

Pharmaceutical Technology
eBook: Trends in Manufacturing, May 2022
May 2022
Pages: 36–38

Citation

When referring to this article, please cite it as F. Mirasol, “Implementing Continuous Bioprocessing: From Theory to Practice," Pharmaceutical Technology Trends in Manufacturing eBook (May 2022).

Articles in this issue
continuous biomanufacturing
Demonstrating a Fully Continuous Bioprocess
Manufacturing OSD Forms: Key Trends Shaping the Industry
Manufacturing OSD Forms: Key Trends Shaping the Industry
Tablet tooling maintenance
Don’t Gamble on Tablet Tooling Maintenance
Tashatuvango/Stock.adobe.com – The struggle to implement continuous biomanufacturing at GMP level is slowly advancing.
Implementing Continuous Bioprocessing: From Theory to Practice
The Lighthouse Effect: Using Technology to Improve Life Sciences Manufacturing
The Lighthouse Effect: Using Technology to Improve Life Sciences Manufacturing
Plan Early: Optimizing Stability During Lyophilization
Plan Early: Optimizing Stability During Lyophilization
Opportunities for Growth and Breakthroughs for Cell and Gene Therapies
Opportunities for Growth and Breakthroughs for Cell and Gene Therapies
Converting Injectable Therapies to Combination Drug-Device Products
Converting Injectable Therapies to Combination Drug-Device Products
Using Robotics in the Aseptic Manufacturing Facility of the Future
Using Robotics in the Aseptic Manufacturing Facility of the Future
Embracing New Realities
Embracing New Realities
Recent Videos
Behind the Headlines episode 6
Behind the Headlines episode 5
Buy, Sell, Hold: Cell and Gene Therapy
Buy, Sell, Hold: Cell and Gene Therapy
Related Content
Communication between the manufacturing plant and retail stores. | Image Credit: © Cagkan - © Cagkan - stock.adobe.com

Circio and Certest to Collaborate on LNP Formulations

Feliza Mirasol
November 21st 2024
Article

The companies will collaborate to create and test circVec DNA–LNP formulations for use in potential therapeutic applications.

Drug Solutions Podcast: Growth and Advancements in Fill/Finish

Drug Solutions Podcast: Growth and Advancements in Fill/Finish

Felicity Thomas
June 25th 2024
Podcast

In this episode, Hanns-Christian Mahler from ten23 Health chats about the advances in fill/finish.

Communication between the manufacturing plant and retail stores. | Image Credit: © Cagkan - © Cagkan - stock.adobe.com

CDMO SEKISUI Expands its CGMP Biopharma Manufacturing Capacity

Feliza Mirasol
November 20th 2024
Article

SEKISUI has used a £15.7 million (US$20.7 million) investment to expand its clinical-grade drug substance manufacturing at its UK site.

Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain

Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain

Jill Murphy
November 14th 2023
Podcast

In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.

Communication between the manufacturing plant and retail stores. | Image Credit: © Cagkan - © Cagkan - stock.adobe.com

Frontier Scientific Solutions Plans a Global Free Trade Zone Gateway to Supply Life Sciences Industry on Back of $1.5 Billion Investment

Feliza Mirasol
November 16th 2024
Article

Frontier Scientific Solutions has unveiled plans to use a $1.5 billion commitment from a major investor to create a global free trade zone gateway to facilitate the life sciences supply chain using Wilmington International Airport in North Carolina.

Communication between the manufacturing plant and retail stores. | Image Credit: © Cagkan - © Cagkan - stock.adobe.com

Newly Opened Innovation Center in New Jersey Gives Avantor Advantage in Solving Life Sciences Challenges

Feliza Mirasol
November 15th 2024
Article

Avantor's newly launched expanded Innovation Center in Bridgewater, NJ, is designed for integrated workflows and features purpose-built collaboration spaces.