Manufacturing Services

The new CGMP facility is expected to contribute to the development of mRNA therapeutics, with a building designed for the CGMP manufacture of mRNA-based in-vivo gene editing, gene-edited cell therapies, protein replacement therapies, cancer vaccines, and infectious disease vaccines.

Forge will provide adeno-associated virus (AAV) process development, toxicology, cGMP manufacturing, and analytical services to Life Bio, which will occur at Forge’s gene therapy facility in Columbus, Ohio called the Hearth.

Advanced continuous manufacturing with modular components is emerging as a preferred platform to produce APIs.

The new agreement is based off the Master Services Agreement that both companies entered in 2021 for the development, manufacture, and supply of rhenium (186Re) obisbemeda, according to a press release.

As new manufacturing processes and technologies are introduced to meet demand and overcome challenges, understanding also needs to improve to ensure the right balance is achieved.

By eliminating the waste involved in traditional approaches to project set-up and execution, integrated project delivery helps innovators in the European life sciences market meet their fast-track delivery targets.

Point-of-use manufacturing may lead to a big change in the accessibility of medicines globally.

Meeting patient needs and achieving high quality are common goals for all stakeholders.

Industry experts share their top outsourcing tips from both the perspective of companies offering outsourcing services as well as for companies looking to outsource.

The researchers will use 3D printing to design novel flow reactors and static mixers.

Experts share best practices in designing, manufacturing, and scaling up dry powder inhaler and metered dose inhaler drug–device combination products for inhalation drug delivery.

Avid Bioservices is building a viral vector development and manufacturing facility near its existing biologics manufacturing facility in California.

Biotage’s new facility in Cardiff, UK, will produce lipids using large-scale flash purification.

Automation offers benefits for sterile manufacturing in 503B outsourcing facilities.

Advances in automation and cleanroom technology improve efficiency for small commercial quantities of aseptically filled drug products.

Aseptic spray drying offers a technology alternative to manufacture thermally stable vaccines.

The deal expands Wavelength’s drug substance manufacturing footprint and its API CDMO business.

Model-based approaches and digital analytics are improving flexibility at both the equipment and the manufacturing-line level.

CDMOs address the unique challenges of liquid and lyophilized forms as well as preparing for the large capacity needed for COVID-19 vaccines.

The UK company is investing £3 million in new instrumentation and equipment to strengthen its high-throughput screening and translational oncology service offerings.

Cytiva is adding process development, media and assay development, and contract development services at its facilities in Korea, Japan, Sweden, and the UK.

Piramal Pharma Solutions invests in expanded potent and non-potent API development and manufacturing at its Riverview, MI facility.

CDMOs strive for flexible, adaptable processes and fast tech transfer for manufacturing investigational drug products, including COVID-19 treatments and vaccines.

Filling and packaging of primary containers is a crucial piece of COVID-19 vaccine and therapeutic production.

The acquisition will give the CDMO additional clinical filling options in Europe, which is expected to come online in 2021.

Understanding of scale-up parameters and use of process analytical technology are important to meet demand for larger batch sizes.

An agreement with Sanofi gives Catalent access to commercial spray drying facility in Haverhill, UK.

GSK announced the opening of its new manufacturing facilities in Singapore after a $130-million investment.

Pharmaceutical Technology and BioPharm International will present a Keynote Session on Meeting Bioprocessing Manufacturing Capacity Demands on Wednesday, April 3, 2019, during INTERPHEX 2019 at the Javits Center in New York City.

Pharmaceutical Technology Europe spoke with Manuel Leal, business development director for Idifarma to learn more about spray drying and how it can support patient-centric drug development.