Pharmaceutical Technology, April 2022
Formulating the Best Approach for Tablets
April 03, 2022
Development
46
4
An early formulation strategy for tablets that is simple and scalable is recommended to ensure fewer downstream problems.
Determining the Best Estimate of Probability of Passing Multiple Stage Tests: Part 2—Dissolution
April 03, 2022
Peer-Review Research
46
4
The author introduces a practical approach to determining the best estimate of probability for passing multiple stage dissolution tests.
Bringing Excipients into the Quality-by-Design Paradigm
April 03, 2022
Development
46
4
Although not easy to do, it is essential because excipients can affect drug-product safety and efficacy.
Early Development Medicinal Chemistry: Utilizing Data and Artificial Intelligence
April 03, 2022
Development
46
4
Experts discuss what data to consider when selecting a high-potential drug candidate and how AI can be harnessed in medicinal chemistry drug discovery.
Breaking Through Barriers to Continuous Manufacturing
April 03, 2022
Cover Story: Manufacturing Trends
46
4
Collaboration and new tools aid efforts to implement new processing technologies for small-molecule drug product manufacturing.
Technology and CAPA
April 02, 2022
Quality/Regulations
46
4
Performing corrective action and preventive action (CAPA) activities is often necessary to investigate a manufacturing deviation and prevent it from reoccurring. Pharmaceutical Technology asked Joe O’Gorman, head of Global Operations at LZ Lifescience, a Cognizant Company, about the role technology plays in performing CAPAs.
Put a Cap on CAPAs
April 02, 2022
Quality/Regulations
46
4
Data may be used to improve (or remove) a corrective action/preventive action.
Cleanroom Cleaning: Proper Methodology and Determining Efficacy
April 02, 2022
Analytics
46
4
Effective cleaning and disinfection along with contamination controls are imperative when operating and utilizing a cleanroom.
A Future Investment
April 02, 2022
From The Editor
46
4
The AMR Action Fund has made its first investments, marking an important step forward for the partnership to achieve its goal of bringing new treatments to the market for priority pathogens.
Expanding Viral Vector Manufacturing
April 02, 2022
Outsourcing
46
4
Pharmaceutical Technology spoke with Colleen Floreck, vice president, Global Marketing and Strategy, Catalent Cell and Gene Therapy about the specific requirements and challenges for expanding production of viral vectors.
Scaling Up Capacity for Cell Therapies
April 02, 2022
Outsourcing
46
4
The booming cell therapy market has created a need for capacity that outsourcing partners are ready to fill.
Understanding Pharmaceutical Compounding from Multiple Perspectives
April 02, 2022
Manufacturing
46
4
Meeting patient needs and achieving high quality are common goals for all stakeholders.
Considering Blow-Fill-Seal for Biologic Drugs
April 02, 2022
Manufacturing
46
4
The continuous, aseptic fill/finish process is finding use in vaccines and biologic drugs.
Regulating Clinical Trials
April 02, 2022
Regulatory Watch
46
4
In January 2022, Europe started to implement EU-CTR, a new regulatory framework for clinical trials, but what does this mean for pharma clinical research?
Meeting Challenges in Solid-Dose Packaging
April 02, 2022
Manufacturing
46
4
Innovations address supply-chain constraints, serialization, and new requirements for sustainable and patient-centric designs.
FDA Maps Strategies to Advance Pharmaceutical Quality
April 02, 2022
Regulatory Watch
46
4
Quality metrics and more domestic production aim to avoid supply disruptions and drug shortages.
Next Level Interrogation
April 02, 2022
From The Editor
46
4
3D cell cultures could provide key avenues to unlocking critical information.
Verifying Compendial Methods
April 02, 2022
Ask the Expert
46
4
Experts Susan J. Schniepp, distinguished fellow for Regulatory Compliance Associates, and Steven J. Lynn, executive vice-president, Pharmaceuticals for Regulatory Compliance Associates, discuss the verification of compendial methods.
Batch High Shear Mixers
April 02, 2022
Product Spotlight
46
4
ROSS Batch High Shear Mixers are a versatile tool for powder delivery and dispersion of low-viscosity liquids.
Modular Liquid Processing Systems
April 02, 2022
Product Spotlight
46
4
The PureVessel series provides modular storage, preparation, treatment, and mixing of liquids.
Dynamic Light Scattering Technology
April 02, 2022
Product Spotlight
46
4
The DynaPro NanoStar II introduces advanced walk-up capabilities in DLS technology.
Updated Process Control Graphics Terminal
April 02, 2022
Product Spotlight
46
4
Rockwell Automations newest graphic terminals increase user storage, product security, and support for modern peripherals.
Major League Moves
April 02, 2022
From the CEO
46
4
Advances in pharmaceutical neuroscience present an opportunity for pharmaceutical companies to stay ahead of the curve.