Universal solution for automated HPLC method development
Shimadzu’s Nexera Method Scouting system provides an outstanding platform for efficient HPLC method development and implementation. It is based on the Nexera X2 next-generation ultra-high performance liquid chromatograph, an all-round LC system for ultra-high-speed analysis.
Shimadzu’s Nexera Method Scouting system provides an outstanding platform for efficient HPLC method development and implementation. It is based on the Nexera X2 next-generation ultra-high performance liquid chromatograph, an all-round LC system for ultra-high-speed analysis.
The Nexera Method Scouting is equipped with two quaternary solvent pumps, a high pressure resistant column switching valve and the dedicated Method Scouting Solution control software to enable automated, quick and simple column and solvent screening. With its solvent blending capability and automated workflow, the system reduces preparation time and the risk of human error to a minimum when setting up the method and analysis schedule manually.
The Nexera X2 UHPLC systems can be used for a wide range of applications, from verifying the purity of synthetic compounds to quantifying their impurities, e.g. in pharmaceutical CMC and drug development/synthesis. In combination with the SPD-M30A photodiode array detector, Nexera X2 offers highly sensitive detection and a large dynamic range for quantification of high and low concentrations in a single experiment.
Method Scouting Solution is the system’s dedicated control software which supports fast and secure operation of the Nexera Method Scouting System. It offers a graphical user interface to simplify the system set up as well as pre-configured system settings conforming to laboratory policies to provide reliable data while minimizing the risk of human error. Connecting between LabSolutions software for data evaluation and the DryLab®4 HPLC modeling software for strategic method optimization enables fast and efficient setup of methods as well as easy calculation and visualization of the design space. In combination with the VALIDAT© toolbox for method validation, the Nexera Method Scouting system provides an all-round solution for highly effective HPLC method development and implementation.
DryLab® 4 is a registered trademark of Molnar Institute of Applied Chromatography
Validat ® is a registered trademark of iCD
For more information please visitwww.shimadzu.eu
Transformations in Drug Development for Cell and Gene Therapies
March 28th 2025As a recognized leader in immunophenotyping for clinical trials, Kevin Lang from PPD discusses how spectral flow cytometry is transforming drug development, particularly in cell and gene therapies like CAR-T. He also dives into his award-winning research, including his 2024 WRIB Poster Award-winning work, and his insights from presenting at AAPS PharmSci360.
Advancing Clinical Trials with Spectral Flow Cytometry: A Conversation with Kevin Lang
March 28th 2025As a recognized leader in immunophenotyping for clinical trials, Kevin Lang from PPD discusses how spectral flow cytometry is transforming drug development, particularly in cell and gene therapies like CAR-T. He also dives into his award-winning research, including his 2024 WRIB Poster Award-winning work, and his insights from presenting at AAPS PharmSci360.
Pharmaceutical Tariffs Are Imminent: How Industry is Bracing for Impact
April 16th 2025On April 14, 2025, the Trump Administration launched a national security-driven investigation into pharmaceuticals, a move that will likely result in tariffs being placed on pharmaceutical drugs, ingredients, and other components that are imported from outside of the United States.
