The 3M Harvest RC clarifier condenses three process steps into a single-stage purification of recombinant protein therapeutics.
The 3M Harvest RC clarifier from 3M Health Care uses a proprietary fibrous chromatography media to condense three process steps into a single-stage purification of recombinant protein therapeutics.
The clarifier provides monoclonal antibody recovery of more than 95% and can be used with cultures with different cell densities, high-packed cell volumes, and cell culture characteristics. The quaternary ammonium functionalized polypropylene fiber, and 0.2 µm PES membrane, provides scalable clarification from discovery to commercial manufacturing scale.
The clarifier introduces chromatographic separation earlier in the process to remove soluble impurities, resulting in cleaner effluent, the company reports.
Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain
November 14th 2023In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.