Sigma-Aldrich to distribute knockout rodents
Scientists at Sigma-Aldrich's new Sigma Advanced Genetic Engineering Labs in St Louis (MO, USA) will develop and distribute genetically engineered animal models for use in research.
Scientists at Sigma-Aldrich's new Sigma Advanced Genetic Engineering Labs in St Louis (MO, USA) will develop and distribute genetically engineered animal models for use in research. The company will reveal the initial animals available as well as its customized rodent development service towards the end of the year.
One of the offerings will be rats with targeted gene deletions, which were first announced in July. The rats will be made using Sigma-Aldrich's CompoZr zinc finger nucleases gene editing technology, which can create rodents with gene deletions in as little as 4 months; a third of the time compared with approaches that use conventional embryonic stem cells, according to information released by the company.
"The knockout rat is a long awaited milestone in the scientific community and we are pleased that Sigma innovation has played such a key role in its development," Dave Smoller, President of Sigma Research Biotechnology, in a press statement. "The potential applications using these rodent models of human disease could ultimately eliminate years of research time and save millions of lives."
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.
Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain
November 14th 2023In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.
INTERPHEX 2025: Use of Walk-In Chambers for Bio/Pharma Development and Manufacturing
April 2nd 2025Sitting down with the PharmTech Group at INTERPHEX 2025, Christopher Murphy, director of Global Business Development and Service Customer Support at Environmental Specialties, discusses the design and critical role of walk-in chambers in the bio/pharmaceutical industry.
