Method Development for Moisture Analysis in Lyophilized Products

Register free: http://www.pharmtech.com/pt_w/lyophilized

Event Overview:

Quality, efficacy and shelf-life of lyophilized pharmaceutical products and ingredients is highly dependent on water content. Routine Karl Fischer (KF) titration is the preferred technique for measuring residual moisture levels compared to other methods such as loss on drying, but, failure to properly optimize solubility and extraction may cause inaccurate water content results.

Attend this webcast to hear Jacob Butler, quality control specialist at Organon Teknika Merck, describe his experience with manual solvent and oven extraction method development. Jacob will present a case study that demonstrates both determination of optimal oven temperatures and how to build an oven method for method validation. Our webcast session will conclude with a live question and answer forum moderated by Kerri-Ann Blake, Product Specialist for Titration at Metrohm. This session will answer your questions and present the latest technology to improve the accuracy of your KF results. 

Key Learning Objectives:

• Learn where to start with method development and optimization of KF titrations

• Hear simple guidelines for improving accuracy of KF results

• Understand how a KF oven can simplify the analysis of water in lyophilized products

Speakers: Jacob Butler, Quality Control Specialist, Organon Teknika Merck

Dr. Kerri-Ann Blake, Product Specialist, Metrohm USA

Time and date: Wednesday, Aug. 14, 2019 at 1pm EDT | 12pm CDT | 10am PDT

On demand available after airing until Aug. 14, 2020

Sponsor: Metrohm

Register free: http://www.pharmtech.com/pt_w/lyophilized