Merck & Co Inc. (Whitehouse Station, NJ) has agreed to acquire two biologics companies: GlycoFi Inc. (Lebanon, NH), a specialist in yeast glycoengineering for $400 million, and the biopharmaceutical company Abmaxis Inc. (Santa Clara, CA) for $80 million.
Merck & Co Inc. (Whitehouse Station, NJ, www.merck.com) hasagreed to acquire two biologics companies: GlycoFi Inc. (Lebanon, NH, www.glycofi.com), aspecialist in yeast glycoengineering for $400 million, and thebiopharmaceutical company Abmaxis Inc. (Santa Clara, CA, www.abmaxis.com) for$80 million.
GlycoFi has a position in yeast-based protein optimization technologythat may be used for developing, producing and commercializingbiotherapeutics. Glycoengineering provides the ability to make proteinssuch as monoclonal antibodies with pre-specified and defined humancarbohydrate chains. Merck says the ability to make such proteins inyeast has advantages of speed, costs, and quality over current methodsof producing monoclonal antibodies and other protein-basedtherapeutics.
Abmaxis is a privately held biopharmaceutical company focused on thediscovery and optimization of monoclonal antibodies. Its antibodyengineering technology platform, "Aisim" (Abamaxis in-silicoimmunization) enables structure-centric computational design followedby experimental selection of human or humanized monoclonal antibodies.
Both deals are expected to close in the second quarter.
Drug Shortages and Complying with FDA’s 21 CFR 211.110 Guidance
April 2nd 2025Susan J. Schniepp, distinguished fellow at Regulatory Compliance Associates, and Rona LeBlanc-Rivera, PhD, principal consultant, Regulatory Affairs at Regulatory Compliance Associates, answer some questions about FDA’s January 2025 21 CFR 211.110 guidance document.
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.