Hovione Launches Screening Service for Spray Dried Dispersions

Article

The service uses Hovione’s Intelligent PROprietary Screening methodology to screen for combinations of polymers, drug loads, surfactants, and solvents with an advanced computational tool.

Hovione, a pharmaceutical spray drying company headquartered in Portugal, announced on Jan. 12, 2021 that it has launched ASD-HIPROS, a proprietary screening service for spray dried dispersions.

According to a company press release, the service uses Hovione’s Intelligent PROprietary Screening methodology to screen for combinations of polymers, drug loads, surfactants, and solvents with an advanced computational tool, which produces scale-independent representative samples of the formulations. The samples are then assessed based on performance and stability.

“ASD-HIPROS is a multiple-step screening service that was perfected in the last 15 years and is able to provide an accurate assessment of spray dried dispersion, in less than two months and requiring as little as [five grams] of API,” said Dr. Filipe Gaspar, Hovione’s Chief Technology Officer, in the press release. “Our accumulated experience and expertise in spray drying were used for the development of this platform. It offers a rational formulation definition using a combination of in silico computational modelling and high throughput formulation testing, maximizing the chances of identifying a winning formulation based on outputs obtained from spray drying prototypes.”

Source: Hovione

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