Early drug formulation and development
Catalent partners with innovators to accelerate programmes through the early phases of development, overcome a molecule’s solubility and bioavailability challenges, and increase its likelihood of success in the clinic.
Modern drugs are becoming more complex and often bring bioavailability and delivery challenges to formulation scientists. By tackling these challenges earlier in the process, and selecting an optimal dosage form at the clinical development stage, costly and time-consuming steps can be avoided later in development, and programmes can be accelerated through the clinic and on towards commercialisation.
Catalent has a broad range of experience and expertise in early phase development, which has seen the company support over 500 INDs. From its facility in San Diego, Catalent supports early phase small molecule development, while its OptiForm® Solution Suite integrates tools and services to deliver relevant data and an optimised development programme; providing an efficient and seamless path from late-stage discovery to phase I clinical trials.
Designed to make it easier and faster for small and mid-sized innovators to develop better treatments, OptiForm Solution Suite includes a comprehensive range of candidate screening tools, ADME considerations, and in silico DMPK modelling, as well as additional bioavailability enhancing tools to provide materials for cGLP toxicological studies, and on to first-in-human studies.
Catalent. More products. Better treatments. Reliably supplied.™
Flexible-Dosage Development Strategies for Today's Clinical Landscape
January 8th 2025This executive summary focuses on dose-flexible manufacturing strategies and their role in drug development. Dose flexibility is increasingly important for early clinical studies, particularly in areas such as pediatric medicines and oncology. However, flexible dosing strategies are often neglected or not prioritized early in development. This presentation will focus on technical strategies that can help anticipate appropriate timing for implementation and how to do so cost effectively while adhering to required timelines.
