Drug Digest: Transferring Energy to Hot Melt Extrusion

In this exclusive Drug Digest video interview, Felicity Thomas, Europe/senior editor, Pharmaceutical Technology Group, interviews Dr. Krizia M. Karry, Global Head of Technical Marketing for BASF Pharma Solutions, about hot melt extrusion (HME) and its use and evolution in drug development. During the chat, Krizia provides insights into how HME is a useful tool for quality-by-design approaches in drug development and manufacturing, talks about what the HME process involves and potential excipient limitations to consider, and highlights interesting active research and HME trends of the future.

Interview featuring

Dr. Krizia M. Karry
Global Head of Technical Marketing for BASF Pharma Solutions

Dr. Krizia M. Karry, Global Head of Technical Marketing for BASF Pharma Solutions, boasts over 15 years of expertise in the pharmaceutical industry. Renowned for her work in continuous manufacturing of solid oral drug products, she has advanced formulation design and optimization, hot melt extrusion processes, and the implementation of Process Analytical Technology (PAT) tools. Her influence extends across leading companies such as Pfizer, Bristol-Myers Squibb, AstraZeneca, and Eli Lilly, where she contributed to new product development. Krizia's insights have made her a sought-after speaker at scientific conferences globally, covering pharmaceutical formulations, continuous processes, hot melt extrusion, and the use of artificial intelligence (AI) in digital formulation design. With numerous published articles and co-authored book chapters, she drives innovation in pharmaceutical technology, focusing on formulations and process engineering for continuous manufacturing, shaping the future of drug delivery and formulation sciences with dedication and excellence.

Sponsors

This episode of Drug Digest is sponsored by:

• Adare Pharma Solutions
• Aprecia Pharmaceuticals
• Thermo Fisher Scientific
• Veltek Associates Inc.

About Drug Digest

Drug Digest is a tech talk video series with the Pharmaceutical Technology® editors, who interview industry experts to discuss the emerging opportunities, obstacles, and advances in the pharmaceutical and biopharmaceutical industry for the research, development, formulation, analysis, upstream and downstream processing, manufacturing, supply chain, and packaging of drug products.

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• April 2024: Stability Testing
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• June 2024: Analytics and Assays