Bioreactor Functions as Perfusion Mimic
Bioreactor Functions as Perfusion Mimic
TAP Biosystem’s ambr micro bioreactor system can be applied as a perfusion mimic to enable scientists to quickly develop large-scale perfusion culture processes of unstable, low producing or minimally expressing proteins or antibodies. This system can be used as a semi-continuous chemostat model for perfusion culture in 10-15 mL micro bioreactors by using the workstation’s integrated cell counter to monitor cell density and calculate both cell growth rates and dilution volumes required to maintain stable cell density. The liquid handling performs dilutions at appropriate time points, which automatically refines chemostasis throughout the culture process. The cell specific performance can then be extrapolated to full-scale perfusion cultures.
Drug Solutions Podcast: Gliding Through the Ins and Outs of the Pharma Supply Chain
November 14th 2023In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.
