Bioreactor Functions as Perfusion Mimic
Bioreactor Functions as Perfusion Mimic
TAP Biosystem’s ambr micro bioreactor system can be applied as a perfusion mimic to enable scientists to quickly develop large-scale perfusion culture processes of unstable, low producing or minimally expressing proteins or antibodies. This system can be used as a semi-continuous chemostat model for perfusion culture in 10-15 mL micro bioreactors by using the workstation’s integrated cell counter to monitor cell density and calculate both cell growth rates and dilution volumes required to maintain stable cell density. The liquid handling performs dilutions at appropriate time points, which automatically refines chemostasis throughout the culture process. The cell specific performance can then be extrapolated to full-scale perfusion cultures.
WMFTS’ BioPure to Showcase Single-Use Bioclamp with Refined Manufacturing at INTERPHEX 2025
April 1st 2025With advanced manufacturing, BioPure’s BioClamp connector is manufactured to be 13% lighter than the previous model, resulting in a 26% reduction in carbon dioxide emissions across the full lifecycle of the product.
Drug Solutions Podcast: A Closer Look at mRNA in Oncology and Vaccines
April 30th 2024In this episode fo the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.
