Stability in mRNA-LNP Formulations
Lipids aren’t the only important ingredients influencing stability and in vivo performance.
Nucleic Acid-based Therapeutics Are Stepping into the Spotlight
The recent success of mRNA vaccines has opened the door for further and future development of nucleic acid-based therapies.
Learning to Think at Lightspeed
Actions combatting the next pandemic must be diverse, reliable, and sustainable.
Managing mRNA Instability
Unique solutions are required to protect inherently unstable messenger RNA.
The Role of Separation Techniques in the Analysis of mRNA Therapeutic Drug Substances and Drug Products
This article reviews a range of techniques available for separative analysis of mRNA therapeutics, their associated impurities, and delivery vehicles.
The Marriage of RNA and Mass Spectrometry
Considerable efforts have been made over the years to resolve the key issues of stability and delivery of RNA-based therapeutics.
Delivering on the Potential of mRNA Therapeutics
The complexity of the RNA production process creates challenges.
The COVID-19 Pandemic and Its Positive Impact on RNA Drug Development
The COVID-19 pandemic helped to showcase RNA molecules and their therapeutic potential. There were also lessons learned in terms of drug delivery, manufacturing, logistics, and storage.
