Pharmaceutical Technology-06-02-2015
Pharmaceutical Technology
Developing an Orally Inhaled Dry Powder Formulation—A Complex Itinerary and a Technological Challenge
June 02, 2015
Formulation
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Successful drug delivery via a dry powder inhaler is determined by the API physicochemical properties, the formulation composition and process, the device and operating conditions, the patient–device relationship, the environmental variables, and ultimately, patient compliance.
Another In-House Operation Gets Outsourced
June 02, 2015
Outsourcing Outlook
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Biopharma companies on both sides of the Atlantic ship more of their assay testing to outside service providers.
Quality Systems Key to Lifecycle Drug Management
June 02, 2015
Regulatory Watch
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Regulators and industry seek to streamline and harmonize oversight of postapproval changes.
Designing Clean Zones
June 02, 2015
Featured Content
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Clearly defined zones of cleanliness must be designed and maintained to prevent product contamination.
New Ways Around Hazardous Reagent Chemistry
June 02, 2015
API Synthesis and Manufacturing
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Safer reagents and reaction conditions are making many hazardous transformations possible.
Industry Expert Q&A with David Fitzhenry
June 02, 2015
Industry Leaders
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Pharmaceutical Technology spoke with David Fitzhenry about the costs of specialty drugs.
Unlocking the Vast Potential of PAT in Solid-Dosage Manufacturing
June 02, 2015
Featured Content
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PAT holds the key to real-time quality assurance and consistent product quality in pharmaceutical manufacturing.
EU’s New Post-Authorization Variations Framework Comes Under Scrutiny
June 02, 2015
Regulatory Watch
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The pharmaceutical industry wants to speed up the variations process by eliminating redundant assessment by different national agencies in the European Union.
Top Trends in Biopharmaceutical Manufacturing: 2015
June 02, 2015
Cover Story
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Pharmaceutical Technology spoke to experts in the field of biopharmaceutical manufacturing to gain insights on top trends that are currently shaping the industry.
Preventing Common Mistakes in Automated Washing
June 02, 2015
Troubleshooting
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Careful choice of wash-water parameters and attention to water quality and basket loading are important for optimal cleaning.
DPI Lab Mixer Increases Efficiency
June 02, 2015
Product Spotlight
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Hosokawa Micron’s Mini Cyclomix lab mixer is designed to blend formulations for dry-powder inhalers without deteriorating the particles.
Conical Tube Reduces Contamination Risk
June 02, 2015
Product Spotlight
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Eppendorf’s Conical screw cap tubes in 15 mL and 50 mL complete a range of volume sizes that meet needs from 0.5 mL to 50 mL.
Ross Multi-Shaft Mixer Reduces Changeover Time
June 02, 2015
Product Spotlight
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Ross’ Multi-Shaft Mixers with interchangeable mixing vessels include an optional cover featuring propeller blades.
Four-Axis Robot Eliminates the Need for Manual Drift Correction
June 02, 2015
Product Spotlight
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Thermo Scientific’s Spinnaker Smart Laboratory Robot, featuring Thermo Scientific Momentum 4 software, is designed to eliminate the need for manual correction of drift by automatically compensating for positional variations.
What’s In a Name? For Biosimilars, A Lot
June 02, 2015
Inside USP
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Will biosimilars share a compendial identity like generic drugs do?
Help Build Better Bio/Pharma Processes
June 02, 2015
From The Editor
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Peer-reviewed papers and technical articles can help advance bio/pharmaceutical development.
Using a Dual-Drug Resinate Complex for Taste Masking
June 02, 2015
Peer-Reviewed
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Box-Behnken modeling was used to optimize a resinate complex, to mask the taste of levocetirizine dihydrochloride and montelukast sodium in orally disintegrating tablets.
Pharmaceutical Technology, June 2015 Issue (PDF)
June 02, 2015
Issue PDF
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Click the title above to open the Pharmaceutical Technology June 2015 issue in an interactive PDF format.