Pharmaceutical Technology-06-02-2015

Successful drug delivery via a dry powder inhaler is determined by the API physicochemical properties, the formulation composition and process, the device and operating conditions, the patient–device relationship, the environmental variables, and ultimately, patient compliance.

Biopharma companies on both sides of the Atlantic ship more of their assay testing to outside service providers.

Regulators and industry seek to streamline and harmonize oversight of postapproval changes.

Clearly defined zones of cleanliness must be designed and maintained to prevent product contamination.

Safer reagents and reaction conditions are making many hazardous transformations possible.

Pharmaceutical Technology spoke with David Fitzhenry about the costs of specialty drugs.

PAT holds the key to real-time quality assurance and consistent product quality in pharmaceutical manufacturing.

The pharmaceutical industry wants to speed up the variations process by eliminating redundant assessment by different national agencies in the European Union.

Pharmaceutical Technology spoke to experts in the field of biopharmaceutical manufacturing to gain insights on top trends that are currently shaping the industry.

Careful choice of wash-water parameters and attention to water quality and basket loading are important for optimal cleaning.

Hosokawa Micron’s Mini Cyclomix lab mixer is designed to blend formulations for dry-powder inhalers without deteriorating the particles.

Eppendorf’s Conical screw cap tubes in 15 mL and 50 mL complete a range of volume sizes that meet needs from 0.5 mL to 50 mL.

Ross’ Multi-Shaft Mixers with interchangeable mixing vessels include an optional cover featuring propeller blades.

Thermo Scientific’s Spinnaker Smart Laboratory Robot, featuring Thermo Scientific Momentum 4 software, is designed to eliminate the need for manual correction of drift by automatically compensating for positional variations.

Will biosimilars share a compendial identity like generic drugs do?

Peer-reviewed papers and technical articles can help advance bio/pharmaceutical development.

Box-Behnken modeling was used to optimize a resinate complex, to mask the taste of levocetirizine dihydrochloride and montelukast sodium in orally disintegrating tablets.

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