Overcoming Common Lyophilization Scale-Up Issues
The same recipe obtained in laboratory-scale equipment cannot, without modifications, generally be used to freeze-dry the product in a pilot-scale or industrial-scale freeze-dryer.
Controlling Nucleation
Ideally, all product formulations should experience the same conditions when it comes to lyophilisation, but in practice, however, nucleation can occur.
The Decontamination Challenge
The increase in aseptic processing driven by the growing number of biologically-derived products has led to an increase in freeze-drying applications in this area at both research and production scales.
Swiss Pharma Strength
Switzerland is an important power in Europe's pharmaceutical industry.
Degradation And What It Means To The Supply Chain
Product degradation is often overlooked compared with other supply chain issues, but if left unchecked can lead to the market entry of substandard medicines, whether through ignorance or gross negligence.
News
The coming years will show a slowing growth rate in the global spending of medicines, particularly when it comes to branded products.
Innovation And R&D In Freeze-Drying
Lyophilisation or freeze-drying is widely used in the pharmaceutical industry for a variety of reasons.
Swiss, Please!
One of the perks of my job is that I can travel to previously unvisited cities. This month, I was lucky enough to be in Switzerland.
Achieving Lean Processing With Single-Use Systems
Single-use filtration and fill–finish technologies can be used as part of a lean manufacturing strategy to boost production, and reduce manufacturing waste and costs.
